US approves 1st drug developed to prevent chronic migraines - Spokane, North Idaho News & Weather KHQ.com

US approves 1st drug developed to prevent chronic migraines

Posted: Updated:
Amgen/AP Amgen/AP

 (AP) - U.S. regulators Thursday approved the first drug designed to prevent chronic migraines.

The Food and Drug Administration's action clears the monthly shot Aimovig (AIM'-oh-vig) for sale. It's the first in a new class of long-acting drugs for preventing migraines. Three other shots are expected to win approval by next year, and several pills for preventing migraines are being tested.

Current prevention treatments include pills originally developed for epilepsy and other conditions and the wrinkle reducer Botox, but many patients abandon them because they don't help much or cause serious side effects.

Amgen Inc. of Thousand Oaks, California, and Swiss drug giant Novartis AG developed Aimovig. Injected monthly just under the skin using a penlike device, the drug will cost $6,900 per year without insurance.

Migraines can cause disabling symptoms: throbbing headaches, nausea and vomiting, and sensitivity to light and sound. About 10 million Americans get them frequently. They're most common in people in their 30s, mostly women, and can last for several hours or even days.

In one study, patients given Aimovig saw their migraine days cut from eight to four a month, on average. Those who got dummy shots had a reduction of two. Each patient group had similar minor side effects, mostly colds and respiratory infections.

Some patients saw their migraines completely eliminated, said Sean Harper, Amgen's research director.

Aimovig and the migraine drugs in development target a substance called CGRP whose levels spike in the blood during a migraine, triggering symptoms.

The long-term safety of Aimovig, also known as erenumab, hasn't been tested, and Amgen plans to track outcomes in women who become pregnant while taking it.

(Copyright 2018 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)

  • Most Popular StoriesMost Popular StoriesMore>>

  • Two injured in Montana after swerving to avoid a kangaroo -- Really

    Two injured in Montana after swerving to avoid a kangaroo -- Really

    Thursday, June 21 2018 12:46 PM EDT2018-06-21 16:46:44 GMT
    File photo of a kangarooFile photo of a kangaroo

    DODSON, Mont. - Two people were injured in Montana Wednesday morning after swerving to avoid a kangaroo on the road.  Trooper Matt Finley with the Montana Highway Patrol said he thought it was a joke when he responded to the call, but when he arrived at about 4 a.m. he saw the kangaroo.  Trooper Finley said he learned there is a kangaroo farm west of Dodson. 

    >>

    DODSON, Mont. - Two people were injured in Montana Wednesday morning after swerving to avoid a kangaroo on the road.  Trooper Matt Finley with the Montana Highway Patrol said he thought it was a joke when he responded to the call, but when he arrived at about 4 a.m. he saw the kangaroo.  Trooper Finley said he learned there is a kangaroo farm west of Dodson. 

    >>
  • Puyallup woman pleads guilty to defrauding $290K from Costco

    Puyallup woman pleads guilty to defrauding $290K from Costco

    Thursday, June 21 2018 12:56 AM EDT2018-06-21 04:56:03 GMT
    Puyallup woman pleads guilty to defrauding $290K from CostcoPuyallup woman pleads guilty to defrauding $290K from Costco
    Federal officials say further testing was unable to confirm the presence of E. coli in the onions and celery used to make chicken salad at Costco warehouses across the country.Federal officials say further testing was unable to confirm the presence of E. coli in the onions and celery used to make chicken salad at Costco warehouses across the country.

    TACOMA, Wash. (AP) - A Washington state woman has pleaded guilty to stealing nearly $290,000 from a Costco warehouse over five years. The News Tribune reports 54-year-old Robin Cline pleaded guilty Wednesday in federal court in Tacoma to charges of wire fraud.  Cline of Puyallup worked at Costco in Fife from 1996 to 2016 as an accounts receivable clerk. She was responsible for processing payments and refunds for customers of the warehouse club operator. Accordi...

    >>

    TACOMA, Wash. (AP) - A Washington state woman has pleaded guilty to stealing nearly $290,000 from a Costco warehouse over five years. The News Tribune reports 54-year-old Robin Cline pleaded guilty Wednesday in federal court in Tacoma to charges of wire fraud.  Cline of Puyallup worked at Costco in Fife from 1996 to 2016 as an accounts receivable clerk. She was responsible for processing payments and refunds for customers of the warehouse club operator. Accordi...

    >>
  • Spokane business owner fed up with feces, unwanted surprise at work

    Spokane business owner fed up with feces, unwanted surprise at work

    Thursday, June 21 2018 2:32 AM EDT2018-06-21 06:32:06 GMT

    A Spokane business owner says enough is enough after finding human feces in front of her doorstep three days in a row. The incidences happened at Neat Old Stuff located at 3rd and Bernard. The shop's owner, CP Phare, has been in the same location for the last decade and says suspicious activity has ramped up in the last year, but nothing like what's been happening over the last few days. "There's like surprise packages usually two-to-three times a week," 

    >>

    A Spokane business owner says enough is enough after finding human feces in front of her doorstep three days in a row. The incidences happened at Neat Old Stuff located at 3rd and Bernard. The shop's owner, CP Phare, has been in the same location for the last decade and says suspicious activity has ramped up in the last year, but nothing like what's been happening over the last few days. "There's like surprise packages usually two-to-three times a week," 

    >>
HD DOPPLER 6i
/
  • Top Stories from KHQHomeMore>>

  • Report: Fire risk to Glacier chalet was 'underestimated'

    Report: Fire risk to Glacier chalet was 'underestimated'

    Thursday, June 21 2018 11:19 PM EDT2018-06-22 03:19:09 GMT

    MISSOULA, Mont. (AP) - A report indicates that fire managers had "underestimated" the risk posed to a Glacier National Park backcountry dormitory that burned last year. The Missoulian reports the investigation report by the National Park Service and U.S. Forest Service notes lessons learned following the lightning-caused fire that damaged the dining hall and destroyed the dormitory of the Sperry Chalet last August. A learning analysis notes that fire staff incorrec...

    >>

    MISSOULA, Mont. (AP) - A report indicates that fire managers had "underestimated" the risk posed to a Glacier National Park backcountry dormitory that burned last year. The Missoulian reports the investigation report by the National Park Service and U.S. Forest Service notes lessons learned following the lightning-caused fire that damaged the dining hall and destroyed the dormitory of the Sperry Chalet last August. A learning analysis notes that fire staff incorrec...

    >>
  • Motorcyclist dies in Hauser collision

    Motorcyclist dies in Hauser collision

    Thursday, June 21 2018 10:43 PM EDT2018-06-22 02:43:50 GMT

    A Spokane man has been pronounced deceased after his motorcycle was involved in a collision on Idaho State Highway 53 in Hauser on Thursday afternoon.

    >>

    A Spokane man has been pronounced deceased after his motorcycle was involved in a collision on Idaho State Highway 53 in Hauser on Thursday afternoon. 

    >>
  • Infant found at Seattle encampment in protective custody

    Infant found at Seattle encampment in protective custody

    Thursday, June 21 2018 10:26 PM EDT2018-06-22 02:26:38 GMT

    A 5-month-old infant found at a Seattle homeless encampment is in protective custody as police investigate child neglect. Seattle Police said Thursday on its blog that the child was removed in late May from an unsanctioned homeless encampment where people were reportedly using methamphetamine.    

    >>

    SEATTLE (AP) - A 5-month-old infant found at a Seattle homeless encampment is in protective custody as police investigate child neglect. Seattle Police said Thursday on its blog that the child was removed in late May from an unsanctioned homeless encampment where people were reportedly using methamphetamine.    

    >>